Orlistat powder

Orlistat poda Base Ruzivo

zita	Orlistat powder
Kufarira	White crystalline powder
CAS	96829-58-2
Assay	≥99%
Solubility	nsoluble mumvura kana doro, soluble muAcetic acid, ethyl ester.
Molecular Weight	495.7 g / mol
Melt Point	50 ° C
Molecular Formula	C9H7ClN2O5
Dosage	30mg
Storage Temp	2-8 ° C Mahara
giredha	Pharmaceutical Grade

 

Zvinoshamisa uye nekukurumidza Kurasikirwa Kwehuremu Mhedzisiro Pane Orlistat Powder

Uchishandisa kuchena 99.7% uremu orlistat upfu hwakagadzirwa kunyatso nyungudutsa mafuta kunyangwe varwere vachiramba kurovedza muviri! Orlistat Powder kubva kuCMOAPI inogadzira yakabudirira kupasa GMP uye DMF certification, chinova chivimbiso chekupedzisira chinogona kuendesa zvigadzirwa zvemhando yepamusoro kune edu ega vatengi. Uye mhando inoshandura yakananga kune vatengi vanofara, kuwedzera kutengesa, uye kunatsurudzwa mufananidzo wechiratidzo.

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Chii chinonzi Orlistat Powder

Orlistat poda mushonga wakagadzirirwa kubatsira varwere kupokana-nekurema, chinhu chinoshanda chiri orlistat, ichibatanidza Orlistat ine yakatariswa yakaderedzwa-koriori uye yakaderera-mafuta chikafu, inogona kuwedzera zvakanyanya kushanda kwayo nekuda kwekugona kwayo kuvhara kunwa kwemafuta mudumbu. Saka yakawanda yehuremu hwekurasikirwa musika iyo inogona kuoneka orlistat poda inoshandisa kudzikisa caloric kudya uye mafuta kuwanda. Semushonga wemishonga, Orlistat inotengeswa pasi pezita rezita "Xenical", zvakare seyakanyanya-iyo-anti-kufutisa mushonga pasi pezita rekutengeserana "Alli".

Zvidzidzo zvekiriniki zvakaitiswa paorlistat poda zvakabvumidza vaongorori vakagadzira fomula kuti vabudise chakasimba kurasikirwa uremu mukomboni kuti mafuta akashata anogadziriswa pakarepo uye mhedzisiro yacho inoonekwa mumavhiki maviri chete. Kuyedzererwa kwesainzi kwaidikanwa kuti uwane chaizvo kuti nei chinhu ichi chichigadzira zvinoshamisa kushaya simba mhedzisiro.

 

Zvinoita Sei Orlistat Powder Basa & Mhedzisiro Inoshamisa

Orlistat poda yakasarudzika inhibitor inovhara ma enzymes ari kuputsa mafuta munzira yekugaya. Kana tikatora kuwanda kwekoriori kudya kunotungamira mukuchengetedza iyo redundancy semafuta, zvinokonzeresa mukuwedzera huremu. Orlistat poda inoshanda nekudzora huwandu hwemafuta muviri unotora kubva kuchikafu. Kamwe ikabatanidzwa kune enzyme yegastric uye pancreatic lipase inogadzira covalent bond iyo inodzivirira ma enzymes kubva kuhydrolyzing mafuta ekudya mumafuta acids uye monoglycerides.

Zvimwe zvidzidzo zvinoratidza kurudziro yeOrlistat poda piritsi ndeye 120 mg, huwandu hwemafuta akavharirwa ingangoita 30% yemafuta ekudya zuva nezuva. Mafuta asina kugayiwa anopfuura nepakati uye anobviswa semarara. Inoshanda nekudzivirira iyo gastric uye pancreatic lipases. Aya ndiwo ma enzymes anoputsa mafuta ezvekudya (triglycerides) muchimiro chinogoneka, mafuta acids kana monoglycerides.

 

Mashandisiro Ekushandisa Orlistat Powder

Murwere anofanirwa kungotora orlistat poda dhizaini nemvura pane yega yega ine mafuta-yakakosha kudya kusvika katatu pazuva uye kusvika paawa rimwe mushure mekudya. Kudya kwega kwega hakufanirwe kuve neanopfuura makumi matatu muzana emakoriori ayo mumafuta.

Sezvo orlistat poda ine chekuita nekudyiwa kwemafuta-akanyungudika mavitamini seA, D, E, uye K, zvinokurudzirwa zvakanyanya kuti varwere vatore akakodzera ezuva nezuva orlistat zvinowedzera kuti vabhadhare chero zvingangokanganisa. Iyo yakakurudzirwa orlistat yekuwedzera yekudyira nguva ingangoita maawa maviri pamberi kana maviri maawa mushure mekutora orlistat.

Iyi fomula ye orlistat poda inoshanda kwazvo pakuburitsa uremu zvekuti varwere vanogona kutanga kuona nekunzwa muviri uchichinja mumavhiki maviri chete! Iyo chaiyo kurapwa ne orlistat Powder inotevera iyo yakapusa mirairo inogona kudzosera makore ekunyanyisa kudya.

 

Chenjedzo Yakakosha Pane Orlistat Powder

Ballance ndiyo yechokwadi kubatsirwa mushure mekushandisa orlistat poda

• Orlistat poda yakagadzirirwa ku batsira varwere kurova kufutisa uye huremu hwakawandisa. Kushandiswa kwaro nevanhu vane chinangwa chekuva mutete zvine njodzi kunofanirwa kudzivirirwa seyakaipisisa uye ine njodzi kuita.
• Kunyangwe kudzikira kwekuda kudya, varwere vari kurapwa Orlistat poda kurapwa vanofanira kutevera kudya kunovaka muviri vasingazvibvise ivo vega zviwanikwa zvakakosha zvinovaka muviri.
• Yakazara pre-kurapwa kuongororwa kuti uve nechokwadi cheyakajairika hutano mamiriro inosungirwa.
• Iyo yakajairika Orlistat poda mhedzisiro mhedzisiro inonyanya kuita gastrointestinal uye kunoitika nekuda kwemafuta asina kudyiwa anodarika nenzira yekugaya.
• Orlistat poda mhedzisiro mhedzisiro inoitika mukati memavhiki mashoma ekutanga ayo manejimendi uye inogona kupera. Zvisinei, zvimwe zviratidzo zvinogona kuramba zvichiramba.
• Mimwe mhedzisiro inogona kukonzerwa neasina kukodzera orlistat poda piritsi, saka kunyatsotevedzera zvakatemwa kunokosha.
• Izvo zvinofanirwa kusimbiswa zvakanyanya kuti kuwedzera Orlistat poda doses hakukonzere kune mamwe masimba ane simba asi zvingangotungamira kune dzimwe mhinduro dzakaipa.

Une mibvunzo? Nyanzvi vedu vari pano uye kupinduraorlistat poda ongororo

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ani Benefits From Orlistat Pchikwereti?

Orlistat poda inobatsira kwazvo kune chero mamiriro anoda kubviswa nekukurumidza uye kunoshanda kwemafuta emuviri akawandisa.

 

1).Kurapa kufutisa kunowedzerwa neOrlistat 
Iine 39% yevagari vepasi rose vanotambura nekuwandisa kwemafuta mumuviri, kufutisa nderimwe rematambudziko ehutano eruzhinji anozivikanwa pasi rese. Njodzi dzinogona kuitika dzinosanganisira, sekushushikana kwemoyo, chirwere cheshuga, mamwe kanzira, uye kuwedzerwa kweropa, kuda kutora matanho anokurumidza uye akakwana - akarongwa, akatarisirwa, uye nekudzora uremu.

Zvirinani, chirongwa chekudzikira uremu chinosanganisira chikafu chakagadzirwa, kurovedza muviri, uye pazvinenge zvakakodzera mishonga, uye inoonekwa seyakabudirira kana zvichikonzera kuonda kwe5% mukati megore.

Orlistat isimba rine simba uye rinoshanda rekuderedza uremu mushonga uyo unoratidzwa kuti unobatsira zvakanyanya mukuzadzisa chinangwa chekurema. Chidzidzo chinosanganisira 3,305 vakawandisa vatori vechikamu vakaongorora mhedzisiro yekupa 120 mg Orlistat katatu zuva nezuva kweana makore mana akabatanidzwa neakaderera koriori, 4% -kudya kwemafuta uye kureruka kwezuva nezuva kurovedza muviri. Mhedzisiro yacho yakaratidza avhareji yekuremerwa uremu hwe30 kg yegore rekutanga. Iyo yekudzikisira uremu hunovimbisa kuti varwere vanochengeta huremu kana kutorasikirwa nehuremu hwakawanda neyakaenderera yehuremu hurongwa.

 

2). Ngozi yerudzi rwechipiri chirwere cheshuga yakaderedzwa neOrlistat 
Tora 2 chirwere cheshuga kana chirwere cheshuga mellitus chirwere chakakomba chinokanganisa glucose metabolism mumuviri. Iyo inosanganisirwa ne insulin kudzvinyirira kana kukwana insulini kugadzirwa nepancreas, uye nekudaro kutadza kuchengetedza iyo chaiyo glucose mazinga mumuviri. Kuregeredza zviratidzo zvekutanga sekuwedzera kwenyota, kurasikirwa kwekurema kusingadiwi, kuneta, kuona kwakashata, kutapukirwa kazhinji, uye maronda anononoka kupora uye kusaataura nawo zvakanaka zvinogona kutungamira kumatambudziko akakomba akadai sehypertension, chirwere chemwoyo, uye chirwere chemwoyo. Naizvozvo, kurapwa panguva yakakodzera uye kwakakodzera kunokosha pakudzivirira kuvandudzwa kweimwezve nyaya dzehutano.

Sesimba rakasimba rekurasikirwa nemushonga, Orlistat poda inoita basa rakakosha mukudzivirira kutanga kwerudzi rwe 2 chirwere cheshuga. Orlistat poda mhedzisiro inogona kuwedzera kushushikana kweinulin, kuderedza postprandial plasma isina-esterified fatty acids, inononoka kana kudzivirira kugaya kwemafuta ezvekudya, kudzora mafuta e-visceral, uye kukurudzira kuvharirwa kweglucagon-kunge peptide-1 mudumbu rezasi mudumbu.

Chidzidzo chevarwere vane kufutisa kunoratidza kuderera kukuru kwezviitiko zverudzi rwechipiri chirwere cheshuga semhedzisiro yekurapwa ne orlistat inoperekedzwa nehupenyu hwakanaka (kudya kwakaderera-mafuta uye kurovedza muviri). Izvo zvakare zvakakonzera mukurasikirwa kukuru kwekurema. Chimwe chidzidzo chakaitiswa nevarume vakafutisa kana vakawandisa vane chirwere chechipiri chirwere cheshuga chaisanganisira manejimendi ye2 mg Orlistat katatu pazuva kwemwedzi mitanhatu kana gumi nemiviri. Pamusoro pekurema kwekurasikirwa, kugadziridzwa kweiyo glycemic kutonga kwakagadzwa, kuderera kwekutsanya plasma glucose (FPG) uye hemoglobin A2c (HbA120c).

Ese masimba akawana data anosimbisa kushanda kwekurapa neorlistat poda, pamwe chete nechikafu chakadzikiswa-chekoriori, yevanorema uye vakafutisa varwere vanoonekwa vane mhando 2 chirwere cheshuga.

 

3). Ropa kudzvinyirira riri pasi pekutonga neOrlistat 
High blood pressure inozivikanwawo sehypertension hutano hutano hunoratidzwa ne systolic blood pressure ≥ 130 mm Hg kana diastolic yeropa ≥ 80 mm Hg uye inobata inopfuura 30% yevakuru vanhu pasi rese. Inozivikanwa seyakanyanya njodzi yezvikonzero zvehutano hwemwoyo senge coronary chirwere chemoyo uye sitiroko asi zvakare inosanganisirwa nekutadza kwemoyo, arrhythmia, chirwere chetsvo chisingaperi, uye kuora mwoyo. Kuvandudzwa kweBP kunonzi kunosarudzwa nemararamiro asina hutano sekushayikwa kwekuita chiitiko chemuviri, uye mamwe mamiriro ehutano seshuga uye kufutisa.

Inhibiting lipase, Orlistat inodzivirira kuiswa kwemafuta ekudya ayo anogona kuvharira tsinga uye mhedzisiro yekukwira kweropa shoma kuderera.

Chidzidzo chekuongorora mhedzisiro ye orlistat yakakonzera kuonda kweropa pavarwere mazana matanhatu negumi nemasere vakaratidza kuonda kukuru pamwe nekudzikira kwese diastolic uye yakasarudzika systolic hypertension semhedzisiro yekupa 628 mg Orlistat katatu pazuva kwegore. Kuderedzwa kwe120 mmHg mune systolic kumanikidza uye 9.4 mmHg mune diastolic kumanikidza kwakanyorwa. Uye zvakare, iyo yakareba-nguva ye orlistat yekushandisa iyo yakawanikwa ichikonzera kudzikira kudiki mukumanikidza kweropa ne7.7 mmHg yeiyo systolic kumanikidza uye 2.5 mmHg yedhiastolic reropa.

Iwo manhamba akawanikwa kubva kuongororo anoratidza mabhenefiti ekushandisa Orlistat yekurapa kweropa kurapwa kwevanhu vakafutisa kana kuwandisa kwevanhu.

 

4). Kuderedza yakazara uye LDL cholesterol ine Orlistat
Yakazara cholesterol ndiyo huwandu hwepasi-density lipoprotein (LDL), yakakwira-density lipoprotein (HDL) cholesterol, uye 20% ye triglycerides. Kuvaka pamadziro emidziyo yeropa kuti iite plaque, LDL cholesterol inoitisa kudzikisira mukati memidziyo uye kudzivirira kuyerera kweropa. Inowedzera njodzi kuhutano uye yakabatana nemamiriro ezvinhu, senge kushushikana kwemoyo uye sitiroko.

Pamusoro pekurema kwekuremerwa mabhenefiti, Orlistat yakanzi ideredze LDL cholesterol.

Chidzidzo chinosanganisira 294 vakafutisa kana vakawandisa varwere vakaongorora orlistat mhedzisiro pahuremu uye serum lipids. Kurapa kwevhiki makumi maviri nemana kwakabatanidza muyero wezuva nezuva we24 mg Orlistat yakakamurwa kuita katatu. Orlistat yakawanikwa ichinyanya kudzikisa huremu pamwe neuzere uye LDL cholesterol. Izvo zvakaramba zvichisimbiswa kuti iyo LDL cholesterol-yekudzikisa mhedzisiro yaive yakazvimiririra neiyo yekuremerwa kurasikirwa kurasikirwa. Imwe ongororo yemwedzi mitanhatu inofukidza varwere mazana mana nevasere yaive yakazvipira kuona cholesterol-kudzikisa mhedzisiro yekudyiwa uremu uye kurapwa orlistat. Mhedzisiro yacho yakaratidza kukosha kwepakati pahuremu hwe360 kg. Pamwe chete neizvozvo, kuderera kukuru muhuwandu uye LDL cholesterol ne6-448 mg / dL yakanyorwa.

Orlistat ine hwakasimba humbowo-hwakavakirwa kugona kugadzirisa mamiriro anogona kuve akananga kana zvisina kunangana nekufutisa uye kuwandisa kwemafuta kuwanda mumuviri. Orlistat mhedzisiro inowedzerwazve kana manejimendi ayo achiperekedzwa nekudya kwakakodzera uye kurovedza muviri kuitira kuti varwere vakwanise kubatsirwa zvizere kubva pakurapwa kunoenderana nezvinodiwa zvavo zvega.

 

Zvimwe Orlistat Powder Ongororo vakaedza

Varwere vakawana yavo Orlistat Kurapa vanofara kutarisa mugirazi zuva nezuva uye voona mhedzisiro inoonekwa seasina kudiwa mafuta, flab, uye cellulite anotanga kupera.

- “Saka muna Gumiguru wadarika ndakaenda kuna chiremba wangu ndikanokumbira rubatsiro sezvo huremu hwangu hwainyanya kundishungurudza. Saka akandiisa pa orlistat uye ikozvino mwedzi mitanhatu pasi pemutsara ndiri 6kg lighter, ndabva pasayizi 16/18 kusvika 20/12. Chinhu chakanakisisa chandakaita. ” - Sez, tora Orlistat Powder kwemwedzi mumwe kusvika kumatanhatu.

- "Ndakatanga izvi paXenical iyo 13.06.20 pa18st 9lbs uye ikozvino ndine 16st 0.5lbs uye ndakarasikirwa ne2st 8.5lbs kusvika ikozvino, hazvishande kana iwe usingadye zvakanaka. Inokukurudzira kudya zvakanaka sezvo uri muchimbuzi nguva dzese kana ukasadya zvakanaka, kusvika zvino zvakanaka! Ichokwadi zvachinja hupenyu hwangu ”- Becks, tora Orlistat Powder kwemwedzi mumwe kusvika kumatanhatu

- “Pandakatanga kutora mushonga uyu ndaive 235lbs uye mune imwe nyaya yemasvondo mana, huremu hwangu hunodzikira kusvika pa4lbs! 220lbs mumwedzi !! Ini handina kana kurovedza muviri, saka chimbofungidzira kuti zvimwe zvakawanda sei zvinogoneka kana ndikazviita… “- Chris, tora Orlistat Powder kwemwedzi mumwe kusvika kumatanhatu.

- "Ndanga ndiri pa orlistat kubva Chivabvu 2021 uye nhasi (Chikunguru 2021) ndakayerwa pakuvhiya kwangu drs ​​uye ndarasikirwa nedombo rechipiri mumavhiki manomwe !! Ndiri kunzwa kunakidza uye ndicharamba ndichishandisa orlistat kuti indibatsire kurasikirwa nehuremu hwangu. Handina kunyatsochinja zvakanyanya muudyiro hwangu kunze kwekunge ndarega kunwa chikafu chisina tsvina! ” - asingazivikanwe murwere, tora Orlistat Powder kwemwedzi mumwe kusvika kumatanhatu.

 

Sei To Choose Orlistat Upfu From CMOAPI

Isu, paCMOAPI, tashanda maawa mazhinji ema lab uye takashandisa izvo zvakaenzana nemari shoma kuti tione kuti Orlistat Powder inosangana nemhando yepamusoro yeindasitiri uye inorarama kusvika kune imwe neimwe inotarisirwa nevatengi. Izvo zvakanakira yedu orlistat poda ndeiyi:

• 7% kuchena
• GMP uye DMF certification
• Yakavimbiswa inochengetedza yepamusoro-soro yekutenda kune yedu Quality Management System.

Ndeapi mabhenefiti ako kubva kushandisa edu Orlists Powder?

• Kuteerana neese indasitiri mirau inoenderana nehunhu hwezvinhu mbishi zvinoshandiswa
• Kununura emhando yepamusoro zvigadzirwa zvekupedzisira
• Kuve nechokwadi chakakosha mhedzisiro yevarwere
• Kugadzira yakanakisa chiratidzo chiratidzo

 

FAQ Pane Orlistat Poda

1.Io Orlistat poda inoshanda here kana murwere asingadye mafuta?

Orlistat poda inoshanda kudzikisa huwandu hwemafuta anopinza mumuviri. Naizvozvo kutora Orlistat nechikafu chisina mafuta hazvishande uye iyo dosi inofanirwa kusvetwa kudzivirira iyo inosanganisirwa orlistat mhedzisiro.

 

2.KUNOGONA XENICAL kutorwa pamwe nemimwe mishonga?  

Kushandisa uyu mushonga nechero ipi yemishonga inotevera kazhinji hakukurudzirwe, asi kunogona kudikanwa mune dzimwe nguva:

• Ropa rakapfava, senge warfarin, heparin, apixaban, dabigatran uye rivaroxaban powder
• Mishonga yeHIV, yakaita se lopinavir, ritonavir, atazanavir, efavirenz, tenofovir uye emticitabine.
• Pfari mishonga
• Cyclosporine
• Amiodarone
• Levothyroxine

 

3.Kureba sei kweXENICAL kurapwa?

Orlistat haifanirwe kutorwa kweinopfuura mwedzi mitanhatu pamusoro pekambani (pane 60 mg dose Orlistat). Kana murwere asina kurasikirwa neinenge 5% yehuremu hwavo mushure mekutora Orlistat kwemwedzi mitatu, kurapwa kunofanira kuenderera.

 

4.Io Orlistat Powder inokonzera kukuvara kwechiropa here?

Orlistat poda haina kuzivikanwa sechikonzero chakakomba chekukuvara kwechiropa mune zvese pre-kiriniki uye kiriniki miedzo. Zvisinei, zvimwe zviitiko zvisingawanzoitika zveOrlistat poda yekukuvara kwechiropa zvakataurwa nevanhu vaishandisa.

Orlistat poda inogona kudzikamisa mashandiro eiyo enzyme yakakosha inonzi carboxylesterase-2 inoita basa rakakosha mukudzikisira chiropa, itsvo, uye nemudumbu wese wemudumbu. Kana iyi enzyme ikadziviswa, huturu hwakakomba hwenhengo dzakakosha hunogona kuitika.

 

5.Kupi kwekutenga Orlistat podapaIndaneti?

Sezvo vagadziri nekisheni vachisiyana, zvigadzirwa zvine orlistat kutengesa zvine mazita eOrlistat emhando dzakasiyana. Iwo madosi ezasi eOrlistat anowanikwa sezita reOrlistat mazita emhando dzakadai sa "Alli" uye "Orlos" uye anogona kurongedzwa zviri nyore pamhepo kubva kune vazhinji Orlistat poda vagadziri nevatengesi.

Kune zvimwe zvinangwa zvehunyanzvi, kushandisa Orlistat Powder nehutsanana hwakanyanya uye hunhu hwakasarudzika hwakakosha zvakanyanya. Nekudaro, kuodha yepamusoro-soro uremu mbishi zvinhu kubva kune vakavimbika vagadziri zvinobatsira.

CMOAPI ndeimwe yeakagadziridzwa Orlistat poda vagadziri vane tsika yenguva refu muindastiri uye inovimbisa akanakisa-emhando yepamusoro uye akapakurwa zvakanaka akawanda orlistat poda.

 

Dzvanya Pano Kuenda Place Yyedu Oorder

Isa odha yako pano kuti utore ye CMOAPI yemhando yepamusoro 99.7% yakachena Kurera Kwekuonda Orlistat Powder yakagadzirirwa kunyungudutsa mafuta. Yedu Orlistat Powder ndeye GMP uye DMF yakasimbiswa, chinova chivimbo chekupedzisira chekuti tinounza zvigadzirwa zvemhando yepamusoro kune edu ega vatengi.

Taura nesu Nhasi
 

References

1. "US orlistat chitaridzi" (PDF). FDA. Nyamavhuvhu 2015. Kudzoreredzwa 18 Kubvumbi 2018. Kuti uwane zvinyorwa patsva ona FDA index peji reNDA 020766
2. Barbier P, Schneider F (1987). "Syntheses ye tetrahydrolipstatin uye mhedzisiro yekugadziriswa kwe tetrahydrolipstatin uye lipstatin". Helvetica Chimica Acta. 70 (1): 196-202. doi: 10.1002 / hlca.19870700124.
3. Bodkin J, Humphries E, McLeod M (2003). "Iyo yakazara synthesis ye (-) - tetrahydrolipstatin". YeAustralia Nhoroondo yeKemistry. 56 (8): 795-803. doi: 10.1071 / CH03121.
4. Filippatos, Theodosios & Derdemezis, Christos & Gazi, Irene & Nakou, Eleni & Mikhailidis, Dimitri & Elisaf, Moses. (2008). Orlistat-Yakabatana Yakashata Mhedzisiro uye Kubatana Kwemishonga. Kuchengetedzwa kwezvinodhaka. 31. 53-65. 10.2165 / 00002018-200831010-00005.
5. Sharma, AM, & Golay, A. (2002). Mhedzisiro ye orlistat-inokonzera kurasikirwa uremu pakudzvanywa kweropa uye nemoyo kurovera kune vakafutisa varwere vane hypertension. Chinyorwa cheBP, 20(9), 1873–1878. doi.org/10.1097/00004872-200209000-00034.
6. Yakarongedzwa nekadiki kari pane kavha, uye bhawa pamusoro pe i (ndokuti, "allī"), asi yakadomwa zvakajairwa musangano.
7. Zhi J, Melia AT, Eggers H, Joly R, Patel IH (1995). "Kuongorora kushomeka kwehurongwa hwekubatisisa orlistat, lipase inhibitor, mune vanhu vane hutano vanozvipira". J Clin Pharmacol. 35 (11): 1103–8. doi: 10.1002 / j.1552-4604.1995.tb04034.x. PMID 8626884.

 

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